CLOSING THE GAP: AN URGENT NEED FOR NEWBORN SCREENING OF ORGANIC ACID DISORDERS IN DEVELOPING COUNTRIES

Organic acid disorders are rare inherited metabolic disorders of key metabolic pathways.For the identification of specific organic acids, investigation of urinary metabolites and genetic testing are required through newborn screening programmes.Delayed diagnosis leads to complications, such as cardiac attacks, respiratory problems, neuro-developmen

The availability of cost-efficient genotyping technologies has facilitated the implementation of genomic selection into numerous breeding programs.However, some studies reported a superiority of pedigree over genomic selection in line breeding, and as, aside from systematic record keeping, no additional costs are incurring in pedigree-based predict